Metal-mediated base pairing in nucleic acids represents a transformative approach wherein traditional Watson–Crick hydrogen bonds are replaced or supplemented by coordinate bonds with metal ions. This ...

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...

Frustrated Lewis pairs (FLPs) created a buzz in the chemistry community a decade ago when they were introduced as a metal-free catalytic system. A research team in Scotland has now taken the concept ...

Identify the independent (manipulated) and dependent (responding) variables in a scientific investigation. Draw conclusions about the relationship between two variables using quantitative data.

An acid-base indicator is a substance that changes color as the pH of the solution changes. Indicators work because they are weak acids which when in solution, exist in equilibrium with their ...

Carnegie Mellon University researchers have developed a synthetic molecule that can recognize and bind to double-stranded DNA or RNA under normal physiological conditions. The molecule could provide a ...

The genome of every cell on Earth uses four DNA bases—adenine, thymine, cytosine, and guanine—to encode proteins. Chemists have long dreamed of expanding that set to create cells that work with both ...

This image illustrates the chemical structure of a purine molecule, highlighting the numbering of the carbon and nitrogen atoms. The purine structure consists of a pyrimidine ring (positions 1 to 6) ...

This lab includes a demonstration of the proper use of a burette system for titrations; including a detailed description, instructional video, and opportunity for students to collect data to ...

A well-established technique, acid-base titration is an analytical method used to determine the concentration of an unknown acid or base. In practice, it involves adding a solution of known strength ...