Super-resolution microscopy image of a mitotic chromosome (white) with the centromeres of each sister chromatid depicted in orange. Each centromere consists of two distinct chromatin subdomains ...

Osaka, Japan – The genetic material inside cells is organized into structures called chromosomes. The centromere is essential for the correct division of the chromosomes via interaction with spindle ...

Researchers at Osaka University say they have clarified the structure of the centromeric region in chicken cells using cryogenic electron microscopy (cryo-EM). The team published its study in “The ...

Researchers from the Kops group in collaboration with researchers from the University of Edinburgh, made a surprising new discovery in the structure of the centromere, a structure that is involved in ...

A genomic study of human and selected nonhuman primate centromeres has revealed their unimaginable diversity and speed of evolutionary change. Although centromeres are vital to proper cell replication ...

Scientists have developed an innovative method to count the number of fluorescent molecules in a cluster and then applied the novel approach to settle a debate rampant among cell biologists —- namely, ...

A team of scientists, including center researchers, is the first to completely determine the sequence in a multicellular organism of a mysterious but essential part of the chromosome called the ...

Figure 1: The pSK41 centromere-like site. Figure 3: ParR–DNA and ParR–ParR interactions in the segrosome. pSK41 parR and parM genes were subcloned into pTTQ18 with C-terminal encoding RGSHHHHHH tags ...

The complete assembly of each human chromosome is essential for understanding human biology and evolution. Using complementary long-read sequencing technologies, we complete the first linear assembly ...

Just like you might use a belt to keep your clothes in place, the centromere holds a pair of chromatids together and attaches it to the mitotic spindle during cell division to ensure that each ...

The centromere is a complex chromosomal structure responsible for proper chromosome/chromatid segregation at meiosis and mitosis. In almost all eukaryotes, centromeres are found at specific locations ...

Some of the most important chapters in fruit flies’ genetic instruction book have finally been decoded. For the first time, researchers have deciphered, or sequenced, the genetic makeup of all of a ...