Anti-citrullinated protein antibodies are a distinctive feature of a subset of patients with rheumatoid arthritis (RA). A new report investigates how lung inflammation in patients with chronic ...

Chemokine citrullination in inflamed joints, and the resultant monocyte recruitment, could accelerate disease progression in rheumatoid arthritis (RA), according to a study by Yoshida et al. published ...

Cancer metastasis is the process by which cancerous cells spread from the primary tumor site to other regions of the body. Despite advancements in cancer research, the factors driving the selective ...

Scientists in Japan may have come across a new ALS gene, according to the February 6 Cell Reports. Koichi Matsuda, University of Tokyo, and colleagues found that the enzyme peptidylarginine deiminase ...

Impact of CAMP Deficiency on Immune Responses and Microbiota in IBD. This illustration depicts the role of Cathelicidin Antimicrobial Peptide (CAMP) in regulating immune responses and microbiota ...

Peptidyl-arginine deiminase 2 (PAD2) enzyme converts arginine amino acid residues in histone proteins into citrulline groups and promotes tumor cell proliferation in pancreatic ductal adenocarcinoma, ...

My research focuses on determining the role of peptidylarginine deiminase (PAD) enzymes in female reproduction and associated diseases. The PAD enzymes post-translationally convert positively charged ...

Chronically stressing the retina can weaken it and damage our ability to see. But retinal cells have a remarkable ability to wall off damage, a team of neuroscientists reports. The walling-off or ...