“When the first draft of the human genome was completed . . . it became immediately clear that while we had the primary sequence of the genome, or we had a draft of it . . . we needed to have an ...

The ENCODE project 8,9 was started by the National Human Genome Research Institute in 2003, with the aim of mapping functional elements of the human genome. The project, later expanded as Mouse ENCODE ...

Looking across evolutionary time and the genomic landscapes of humans and mice, an international group of researchers has found powerful clues to why certain processes and systems in the mouse - such ...

Screening of a bacteriophage λgt11 cDNA expression library with a polyclonal anti-microtubule associated protein (MAP) antiserum resulted in the isolation of two non-cross-hybridizing sets of cDNA ...

The best-laid plans of mice and men / Often go awry — Robert Burns If mouse models of human disease are used incautiously, the best-laid plans of researchers might also, as the poet said, go awry.

For years, scientists have considered the laboratory mouse one of the best models for researching disease in humans because of the genetic similarity between the two mammals. Now, researchers at the ...

We humans have more in common with mice -- at least genetically speaking -- than you might think, which is why they are such good substitutes for us in medical research, new studies have confirmed.

Looking across the genomes of humans and mice, scientists have found that, in general, the systems that are used to control gene activity in both species have many similarities, along with crucial ...