A small molecule known as 10H-phenothiazine reduced the loss of motor neurons, the nerve cells that are lost in SMA, in ...

Each brain is unique, not only in its connections but also in the molecular composition of its neurons, particularly ion channels. Despite their variability, the brain functions reliably -- a paradox ...

Neuronal degeneration is the most severe long-term consequence of repetitive seizures in patients with epilepsy, which until now was thought to be primarily caused by excitotoxicity, or ...

A new study suggests that how neurons process energy may determine whether they resist damage or begin to break down.

A new drug-free, minimally invasive intervention targets the root cause of progressive loss of neural function in spinal ...

Overactivation of dopamine neurons may directly drive their death, explaining why movement-controlling brain cells degenerate in Parkinson’s. Mice with chronically stimulated neurons showed the same ...

SMA pathology affects a wider range of cells, including astrocytes and microglia, beyond alpha motor neurons. Advanced techniques revealed significant ventral horn neuron loss and abnormal morphology ...

Spinal muscular atrophy (SMA) is a severe neurological disease for which there is presently no cure, although current therapies can alleviate symptoms. In the search for better treatment options, ...

Within the human brain, a region known as the left angular gyrus and the way that it “tracks time” have emerged as a crucial player in the development of Alzheimer's disease. Tokyo, Japan - ...