Listen with Speechify 0:00 1:00 by Lewis Cantley Click on the enzyme names or on the the arrows to follow the PIP pathway. Please download the Adobe Flash Player to view this content: From Kinase to ...
The PI3K/PDK1/Akt signaling axis is centrally involved in cellular homeostasis and controls cell growth and proliferation. Due to its key function as regulator of cell survival and metabolism, the ...
Phosphatidylinositol 3-kinase (PI 3K) acts upstream of myriad cellular pathways, including those that regulate protein synthesis and tumorigenesis. In this example, PI 3K phosphorylates the lipid PI ...
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