Final, 247th participant randomized and commences treatment in Actinogen’s XanaMIA pivotal phase 2b/3 Alzheimer’s trial

Topline final safety and efficacy results for the full 36 weeks of treatment from all participants will be available in ...

Special breathing tubes don't improve emergency intubation outcomes, trial finds

Modified endotracheal tubes designed to reduce patient pneumonia risk failed to improve outcomes compared to standard ...
Open Heart

Mineralocorticoid receptor antagonists for acute myocardial infarction: a systematic review and meta-analysis of randomised controlled trials

Background The role of mineralocorticoid receptor antagonists (MRAs) in acute myocardial infarction (MI) remains ...
BMJ Open

Prospective randomised controlled trial of the use of nasogastric tubes in patients with adhesive small bowel obstruction (ASBO): protocol for the NASBO study

Introduction Nasogastric tubes (NGTs) are standard practice in the management of adhesive small bowel obstruction (ASBO). Their insertion can be associated with significant patient discomfort and ...
BioSpace

CAR-T Developers Will Need Randomized Trials as FDA Eyes Tighter Approval Requirements

For traditional approval, CAR T therapies will need to establish superiority over current standard treatments, including ...

MIMEDX Provides Update on EPIEFFECT® Randomized Controlled Trial

Publication of Interim Results and Presentation at Recent Industry Event Demonstrate Clinical Benefit Associated with Use of ...
BMJ Open

Pilot randomised controlled trial of the self-help plus stress management intervention among patients with breast and gynaecological cancer in Viet Nam: a study protocol

Introduction Implementation of low-intensity, evidence-based psychological interventions can help meet the mental health and ...