Rhodopsin, a pigment of the retina that is responsible for perception of light is also involved in temperature sensation. The work emerged from a collaboration between the laboratory of Andrew Chess, ...

The P23H mutation within the rhodopsin gene (RHO) causes rhodopsin misfolding, endoplasmic reticulum (ER) stress, and activates the unfolded protein response (UPR), leading to rod photoreceptor ...

Sammons J and Gross AK. 2012 In vitro biochemical assays to monitor rhodopsin function. Methods in Molecular Biology, in publication. Hollingsworth TJ and Gross AK. Defective trafficking of rhodopsin ...

Animals can adapt their ability to see even with extreme changes in temperature, researchers have discovered. The researchers looked deeply into the eyes of catfish living in cold-water streams at ...

Retinitis pigmentosa is the most prevalent form of congenital blindness. Using a retinitis pigmentosa mouse model, researchers have now shown that targeted activation of genes of similar function can ...

Retinitis pigmentosa is the most prevalent form of congenital blindness. Using a retinitis pigmentosa mouse model, researchers from Ludwig-Maximilians Universitaet (LMU) in Munich have now shown that ...

As many as 40,000 people in Germany suffer from retinitis pigmentosa. This hereditary disorder is characterized by loss of photoreceptors in the retina, and can be caused by mutations in many ...