Continuous roller compaction has been a well-established method in the pharmaceutical business for decades, and it is used for more than just moisture and temperature-sensitive products. Unlike ...

Dry granulation, also called roller compaction, has been a popular method in recent years and has many applications. The powder is compressed between revolving rollers to generate flakes. The flakes ...

There are significant benefits to dry granulation, in terms of cost-reduction and processing, and it can be used with sensitive materials. However, there is little indication as to which process ...

Granulation is a critical unit operation in pharmaceutical manufacturing, where fine powders are agglomerated into granules to improve flow properties, uniformity, and compaction performance. The ...

Dry-powder cell-culture media (CCM) offer many advantages with respect to shipping and storage due to their reduced volume and increased stability. However, such media need to be highly soluble and ...

In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...