NFL Week 16 is here, so let's look at the odds and make some picks and predictions for the coming weekend as the playoffs near.

Steelers vs Lions Best bet: Lions team total Over 29.5 (-125) The Detroit Lions are fifth in the league in offensive DVOA, and they tend to play better indoors on the fast surface at Ford Field. They lead the NFL in points per game (30.6) with that number ticking up to 33.7 ppg at home.

Get the latest odds, analysis, predictions, picks, and best bets ahead of kickoff between the New England Patriots and Baltimore Ravens in Week 16.

The San Francisco 49ers and Indianapolis Colts meet for Monday Night Football at Lucas Oil Stadium in Indianapolis, Indiana. Kickoff is at 8:15 ET.

Other highlights this weekend include two division matchups on Saturday (Eagles-Commanders and Bears-Packers), followed by a handful of must-see games on Sunday, including Bucs-Panthers, Jaguars-Broncos and Patriots-Ravens. Below, let's see if we can stay above .500 and carry some momentum into the second-to-last weekend of the regular season.

The Philadelphia Eagles could clinch the NFC East on Saturday, as they just need one win to eliminate the Dallas Cowboys from the playoffs. Jalen Hurts and comp