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  1. Melatonin: What It Is, What It Does & How It Works - Cleveland Clinic

    Melatonin is a natural hormone that’s mainly produced by your pineal gland in your brain. It plays a role in managing your sleep-wake cycle and circadian rhythm.

  2. Melatonin: Benefits, Uses, Side Effects and Dosage - Healthline

    Feb 25, 2025 · Melatonin may improve sleep, eye health, and seasonal depression. It’s generally considered safe and has few side effects, but is not recommended for children. Melatonin is a …

  3. Melatonin | Description, Hormone, & Effects | Britannica

    Nov 8, 2025 · Melatonin plays a crucial role in regulating sleep cycles by detecting light and dark through the retina. It binds to its receptors on the pituitary gland and the ovaries and appears …

  4. Melatonin: What You Need To Know | NCCIH

    What is melatonin and how does it work? Melatonin is a hormone that your brain produces in response to darkness. It helps with the timing of your circadian rhythms (24-hour internal …

  5. Melatonin - Mayo Clinic

    Aug 13, 2025 · Melatonin is a hormone in your body that plays a role in sleep. The production and release of melatonin in the brain is connected to time of day, increasing when it's dark and …

  6. How Does Melatonin Work for Sleep? - Verywell Health

    Mar 31, 2025 · Melatonin is a naturally occurring hormone produced by a gland in the brain. It regulates your circadian rhythm (the body's natural 24-hour internal clock) and helps with sleep.

  7. Melatonin Sleep Aid Supplement: Effectiveness, Dosage, & Side ... - WebMD

    Sep 13, 2024 · It helps your body know when it's time to sleep and wake up. Normally, your body makes more melatonin at night. Levels usually start to go up in the evening once the sun sets. …

  8. Melatonin: Benefits, Uses, Side Effects, and More - Health

    Dec 9, 2025 · Melatonin helps regulate sleep-wake cycles and may have benefits for insomnia and jet lag. Short-term use is safe, but long-term effects need more study.

  9. What Does Melatonin Do? Understanding its Role in Sleep - Sleep ...

    Jun 20, 2025 · Melatonin is commonly known as the body’s natural sleep hormone and plays a central role in regulating circadian rhythms, which control the natural cycle of sleep and …

  10. Melatonin: beyond circadian regulation - exploring its diverse ...

    Aug 1, 2025 · As an indoleamine with a long evolutionary history, melatonin's physiological functions have evolved from its initial role in regulating skin pigmenta…